Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
The Veterans Day holiday, which pays tribute to all men and women who have served in the U.S. military, dates back to 1919, when President Woodrow Wilson proclaimed November 11 as Armistice Day to celebrate the end of fighting exactly one year earlier in World War One - "the war to end all wars" - between Germany and the allied nations of Britain, France and the United States. The armistice famously went into effect at "the eleventh hour of the eleventh day of the eleventh month."
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Since merged airlines often continue to report delay statistics separately, it may take a few years to see how the new American does during holiday travel.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Some industries will likely pick up faster than others. Industries such as construction and manufacturing will probably begin to hire sooner. Retail, tourism, and hospitality, which depend entirely on consumer spending, will probably be among the last to recover.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Graduates in economics and finance still have great prospects for making big money, the National Business Daily reported, citing a new survey. The average monthly salary for graduates from five major Chinese universities in finance and economics stayed above 10,000 yuan.
Trends and targets in antiviral phototherapy
'In the next 12 to 24 months, unless any of these bottlenecks are solved, we could see WTI going down to $50 a barrel, to incentivize producers to slow down,' she said
8.Form or Join a Study Group
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Mr Lam predicts that any recovery in the market will rely on appetite from cash-rich companies from mainland China, with foreign investors restricting their investments to real estate investment trusts or stocks exposed to developers, rather than actual property.
ACE2 as a potential therapeutic target for pandemic COVID-19
13. “Girlhood” (Céline Sciamma)
Diagnostic technologies for COVID-19: a review
The board is frequently covered in equations. Have you ever wondered what those equations mean? Well, we may never know what they mean, but they are all real, accurate equations. Very impressive, Big Bang. Very impressive indeed.
Chinese exports rose at more than twice the rate expected in November, boosting the country’s trade surplus.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Men and women rated the strengths of their programme equally.
The diplomatic row began when Ankara’s foreign minister was denied entry to the Netherlands on Saturday for a campaign rally in favour of Mr Erdogan’s constitutional reforms. Armed Dutch police also intercepted another Turkish minister, Fatma Betul Sayan Kaya, on her way to the rally in Rotterdam and escorted her back to the German border.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
在9月初发布的另一份报告中，世界气象组织(World Meteorological Organization)称，2013年大气中的二氧化碳水平，比工业革命之前的普遍水平高出42%。其他重要的温室气体含量也有所增加，与前工业化时代水平相比，甲烷增加了153%，一氧化二氮增加了21%。
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
adj. 投影的，投射 v. 投射（project的过去
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
10) I often make a fuss about unimportant things 0 1 2 3 4
This post is in partnership with Entrepreneur. The article below was originally published atEntrepreneur.com.
China's employment situation is generally stable in the first quarter of 2016, said Li Zhong, Spokesman of the Ministry, adding that the economic downturn and structural reform, however, make employment more difficult.
Influenza neuraminidase: A druggable target for natural products
Over at Huffington Post Mark Gongloff warns: That 'dramatic downgrade of U.S. economic growth in the first quarter revealed the economy's lingering weakness, exposed the folly of Washington's austerity obsession and slapped the Federal Reserve's newfound optimism right in the face.' And with politics deteriorating, it'll get worse.
Don't accept an Offer Accept Immediately
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
STEP 10: Even if you don't really fit the criteria, tell everyone you are a SOCIOPATH
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
Finding the skill sets and attitudes that support the culture of the brand you want to promote will foster innovation and enhance your reputation. Include folks from outside the company for the people you rely on. That will start a free marketing chain reaction that can build confidence and revenue.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
12. 最有希望的迹象。有段时间，你会觉得现状已经改善了，人们可以公开大声谈及业内的歧视现象。维奥拉·戴维斯(Viola Davis)出来说话，詹妮弗·劳伦斯(Jennifer Lawrence)公开谈起，自己比片中的合作男星片酬少。“我不想被视为‘难搞’或者‘被宠坏了’，”她在简报《伦尼》(Lenny)中为许多人发言，其中包括许多薪酬更低的人们。
To Anita Eerland and Rolf Zwaan [THE NETHERLANDS] and Tulio Guadalupe [PERU, RUSSIA, and THE NETHERLANDS] for their study “Leaning to the Left Makes the Eiffel Tower Seem Smaller."
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Many are less than impressed by the cheesy indulgence, with the New York Daily News speaking to one dietitian who blasted the lack of nutritional value in the pizza's most expensive ingredient: the Ecuador-imported gold flakes.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Today's and tomorrow's technology sits on top of multiple layers, every one of which is changing and has to inter-operate with others. This makes our gadgets, the internet of things, phones and laptops unstable. And it makes consumers irritated. How many of your apps actually work--and actually make life easier, faster or more fun? I'd expect to see consumer cynicism grow, as delight is overtaken by disappointment. This will put pressure on hardware and software developers to deliver that most boring of qualities: reliability.
Inhibition of SARS coronavirus helicase by bismuth complexes
PBS' 'Vietnam War' series receives a special award.
5. Life is like a coffee table: it’s got tea sets and dinnerware all over it. (beiju, 杯具, is a homophone for tragedy, 悲剧, and dinnerware, canju, 餐具, a homophone for disaster, 惨剧).
Blue skies will not be, and should not be, a luxury.
The research also suggests there maybe a value in finding a job through an internship. Interns who accepted a job offer had higher salaries than those who had received an offer but refused it. Those interns who did not receive an offer had lower salaries still. The gap between these groups had increased three years after graduation.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
"It became an issue about so many things, such as the environment, energy, workplace disasters and the role of big government. It became a lightning rodfor peoples' anxieties," she explained.
Among these six US schools, Rutgers Business School in New Jersey is the highest new entrant at 70. WP Carey School of Business at Arizona State University is the highest returning school at 57. Moore School of Business at the University of South Carolina returns at 77. Moore stands out for being top overall for international course experience. Its students spend from several months to a year overseas.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Countrywide, month-on-month prices rose in 59 out of 70 cities last month – down from 62 – were unchanged in four and fell in eleven. Cities where prices fell from the previous month included Shenzhen (down 0.3 per cent), Hangzhou (down 0.4 per cent) and Xiamen (down 0.2 per cent).
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
“This is a historic moment for Puerto Rico,” said 50-year-old Jose Davila as he waved a large flag from Rossello’s pro-statehood party. “He’s the hope of our island, he’s the hope for statehood, he’s the hope for a people that have suffered.”
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
The remarks by Recep Tayyip Erdogan come less than 24 hours before Dutch voters go to the polls in a national election that has been coloured by a heated debate about the role of Islam in Dutch society, spurred by anti-Islam candidate Geert Wilders. Mr Wilders’ Freedom party (PVV) is polling second in the race.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
“I was quite sceptical initially in doing an online course but the communication and online interaction were perfect,” says one graduate from AGSM.
However, another 876 jobs being offered have not registered a single applicant as of Tuesday, according to Zhonggong. For instance, nobody has so far shown any interest in becoming a railway police officer in Shanghai and Xi'an.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
That's not even a sarcastic quip, it's the truth.
The future is always bright if you are an entrepreneur, and the opportunities to create new ventures based on the digitisation of age-old services has a long way to run.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
It Pays to Get Along
The results are based on a survey of 15,870 people across the country in August and September.
We think of the passage of NBA time in seasons, for obvious reasons. There's connection, a continuum. It's how we remember things that happen, in the course of a season of play. But there's some benefit to looking back at a calendar year, January 1 to December 31, and what we've learned in that process. After all, many say the "unofficial start" to the NBA season is Christmas, with the new year starting soon after. So here are the lessons we learned about the NBA in the year 2017.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
We will continue to transform government function.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Financial advisors and asset allocators who had been hoping to see some benefit this year from tactical strategies were also not spared the punishment of a capricious market. Of the top three tactical strategies in the country (Mainstay Marketfield, Good Harbor U.S. Tactical Core, F-Squared Premium AlphaSector Index), two had nearly imploded with double-digit losses while the third found itself under SEC investigation for misleading the public about its historical returns. The other giant tactical manager, Schwab’s $9 billion Windhaven Diversified Growth product, looks to end 2014 with a return close to zero. So much for tactics.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Here are five things consumers and investors can count on (probably) in 2015:
File this under "great, yet stupid gift ideas." The BOx bottle opener claims to be the "world's first smart bottle opener" but it's not groundbreaking. This bottle opener sends a message to your friends via Messenger every time you open a bottle — crazy, right?
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
A modular microarray imaging system for highly specific COVID-19 antibody testing
About 980 million yuan of illicit assets were recovered, according to the Communist Party of China Central Commission for Discipline Inspection.
For the first time a Bond girl’s storyline will be followed beyond her fleeting experience with 007, with the return of Pussy Galore.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
'My first duty, my first responsibility was to be true to the original feel of the book, to be true to Ian Fleming: his creation, his world and his ideas.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Dachis says: Adidas added more than 34 million new fans and followers in just 12 months this year. The company put that audience to good use and benefited from high levels of positive discussion all year long.
8.Prosthetic Hands That Sense Touch
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
The surviving cat, since named Trooper, has recovered and found a new home.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
活跃的ETF市场将取决于基于收费的分销网络的发展。富达国际(Fidelity International)亚太区董事总经理陶博宏(Mark Talbot)表示，分销基础设施正抑制零售需求。
And this year, the Nobel Prize has defied the convention of celebrating big by presenting the biggest prizes to discoveries on the smallest scales.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
With interest rates expected to rise only slowly, commodities are likely to attract hedge funds and other speculative investors looking for juicier returns, said the bank.
A facile assay for rapid detection of COVID-19 antibodies
1. China’s leadershipwill ignite the capital economy, funding an aggressive growth program withmajor infrastructure investments to support urban development, including hugeallotments for housing, schools, roads, and more.
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
3. Dan Weiss “Fourteen” (Pi Recordings) There’s so much in “Fourteen,” the album-length composition by the drummer Dan Weiss: meticulous chamber maneuvers; avant-garde yowling; wordless vocals of new-music and northern Indian pedigree. More impressive than the expansive frame of reference is the fact that Mr. Weiss, marshaling about a dozen of his peers, spins it all into a flowing fabric.
In the foreseeable future, China will see the boom of enterprises in tertiary industry. Related majors, including law, journalism and communication, and management, are expected to play a bigger role, according to the report.
New Year should be a time of banked-up fines, the scent of flowers and wine, good talk, good memories and loyalties renewed. But if all else is lacking - love will do.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Zhou Qunfei from Lens Technology, the major touchscreen maker, ranks third on the list with a net worth of 45 billion yuan.
他在最后一刻选择了教育慈善机构Teach First，后者如今已经成为英国招聘新毕业生最多的机构。雷文斯克罗夫特没有空降至需要重组的公司，而是开始在波尔主教学校(Cardinal Pole School)教授商业和经济学，该校主要招收伦敦东部哈克尼区(Hackney)11岁至19岁之间的青少年。
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
I experienced this pessimism personally in Davos in January 2014. Several leading western intellectuals asked me whether war would break out between China and Japan. I was so confident that there would be no war in east Asia that I offered to take bets with ten-to-one odds against myself with eminent western journalists. Two took up my bets. And I will be collecting on these bets when I return to Davos in January.
Three leading energy agencies recently said production from outside the Organization of the Petroleum Exporting Countries would increase this year, much of it from U.S. shale. Added to that is the possible return to market of millions of Middle East barrels as Iran, Iraq and Libya potentially ramp up production. All of that is set to press on prices.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
It’s wall-to-wall pure pop heaven, crackling with originality and dark humor, teeming with action sequences so perfectly timed and executed you almost want to run out of the theater on the spot so you can call a friend and rave about it — but you wouldn’t dare leave your seat because you wouldn’t want to miss a frame of this brilliant, pulse-quickening gem.
1. Buy expensive tailored clothing that only sort of fits so that most of the time your buttons appear to be just seconds from bursting.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
PBS' 'Vietnam War' series receives a special award.
This founding father argued that the college would both guard against the desire in foreign powers to gain an improper ascendant in our councils and ensure the office of President will never fall to the lot of any man who is not in an eminent degree endowed with the requisite qualifications.
Length-scale dependence of protein hydration-shell density
Xinhua reported in 2015 that the MOE and five other central government departments were putting together a task force to ensure that football thrives in the country's schools.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
About this collection
Goldie Blox是一家玩具公司，使命是重新定义玩具商店中的“粉红走道”。在科学、技术、工程和数学（STEM）教育和职业领域，男性数量要大大多于女性，大部分女孩往往在八岁前就对这些领域失去了兴趣。Goldie Blox所设计的玩具则通过吸引女孩发展强大的口头及故事讲述能力的方式——同时仍提供机会来发展日后可转化成对工程学兴趣的技能——来鼓励和启发未来的工程师们。说到机会，一家玩具初创企业如何能在和一开始就统治着玩具行业的大公司的抗衡中脱颖而出呢？Goldie Blox走出了明智的一步：最近，该公司发布了一段视频，采用了Beastie Boys的歌曲《女孩们》（Girls）做背景音乐，该视频得到了病毒式传播。尽管这段视频最终被撤下，但Goldie Blox在提高公众对让更多女性和女孩对STEM产生兴趣——以及对Goldie Blox玩具——的认知上，做了一份相当不错的工作。
It also said 98 percent of government-sponsored students returned to China. Government-sponsored students who study abroad have chosen to pursue disciplines most needed in China, including engineering, the pure sciences, agriculture and medical science.